This study retrospectively analyzes the clinical nursing of a patient with postpartum hemorrhage complicated by postpartum heart failure, exploring nursing strategies for such cases. In addition, it introduces care methods based on the Enhanced Recovery After Surgery (ERAS) concept, focusing on psychological support and the recovery of postpartum physical function. The patient underwent forceps-assisted vaginal delivery due to acute fetal intrauterine distress and delivered a female infant. Postpartum hemorrhage of 1,000 mL occurred. At 1 hour and 38 minutes postpartum, the patient suddenly experienced chest tightness, choking, dyspnea, and coughing without pink frothy sputum. A multidisciplinary emergency response was immediately initiated. Within 2 hours postpartum, the patient developed heart failure, likely related to the administration of uterotonic and vasoconstrictive hemostatic agents and rapid intravenous fluid infusion, which increased cardiac load and triggered heart failure. Following meticulous treatment and nursing care, the patient recovered and was discharged. With adherence to a series of guided interventions, her postpartum physical functions achieved satisfactory rehabilitation.

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Background: Copper ions play multiple roles in cancer metastasis and invasion. Breast cancer prognosis and immunotherapy efficacy are intricately linked with genes associated with copper metabolism. Studies have shown the therapeutic potential of eliminating or overloading copper ions in cancer. Further study is needed to elucidate the correlation between copper ion metabolism and cancer progression. Methods: Based on The Cancer Genome Atlas (TCGA) dataset, this study first performed univariate COX regression and LASSO regression analyses on 111 copper metabolism-related genes. Subsequently, patients were stratified into high- and low-risk groups, and systematic comparisons were conducted between the two groups in terms of clinical stratification, immune cell infiltration, tumor mutational burden, and predicted immunotherapy response. To further validate the clinical relevance of the model genes, this study analyzed their protein expression patterns using the Human Protein Atlas database and performed immunohistochemical experiments with clinical breast cancer tissues and matched adjacent normal samples for confirmation. Results: A prognostic model was created to predict using the lasso-Cox regression results and the genes DLAT, SLC31A1, LOXL1, and MTF1. The low copper metabolism gene score group showed better survival outcomes, while the high copper metabolism gene score group was associated with enhanced immunotherapy response. Immunohistochemical staining revealed high DLAT, SLC31A1, LOXL1, and MTF1 protein expression. Conclusion: This work highlights the profound impact of copper metabolism on breast cancer biology, linking it to patient survival, immune landscape, and therapeutic response. These insights have direct implications for developing predictive biomarkers to guide personalized immunotherapy. The results provide a new perspective for breast cancer treatment and may offer a basis for optimizing diagnosis and treatment strategies.

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Hashimoto's Thyroiditis (HT), as the primary cause of hypothyroidism worldwide, has shown an increasing prevalence. Although Western medicine can regulate thyroid function, its effect on reducing autoantibodies is limited. Based on the holistic concept and syndrome differentiation and treatment, Traditional Chinese Medicine (TCM) has demonstrated unique advantages in regulating immunity, improving symptoms, and delaying disease progression. By sorting out the etiology, pathogenesis, main treatment methods, and efficacy of HT, this paper aims to explore the progress of TCM in the treatment of HT and provide ideas and methods for clinical practice. However, there is a lack of high-quality clinical evidence for TCM treatment of HT. In the future, high-quality clinical trials are needed to confirm the efficacy, so as to promote new breakthroughs in TCM treatment of HT.

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Gout is a metabolic disease caused by the deposition of monosodium urate, marked by severe pain and inflammation. Globally, its incidence rate is on the rise, and the incidence population is getting younger, which has become a key public health problem. The treatment methods of Western medicine can quickly exert anti-inflammatory and analgesic effects, but cannot cure the disease. Traditional Chinese medicine has become a potential treatment for gout. From the perspective of traditional Chinese medicine's principle of syndrome differentiation and treatment, Chinese medicine can regulate the organs of the body, improve metabolic disorders at the root, reduce the production of uric acid, and promote its excretion from the body. Chuanxiong, as a traditional Chinese medicine, has a synergistic effect of various active ingredients such as ligustrazine and ferulic acid, which can alleviate pain, reduce inflammation, reduce urea, improve microcirculation, and have antioxidant effects. It is used to treat gout. In the future, the mechanism of action of Ligusticum chuanxiong in treating gout can be exploited through the development of combination drugs, and a new treatment strategy can be created, providing reference for further research on the pathogenesis of gout and the development of new drugs.

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