Correlation between thrombus volume, neurological deficits and clinical prognosis in patients with acute ischemic stroke undergoing mechanical thrombectomy

Nursmangul Sidik

doi:10.54254/3049-5458/2026.35109

Abstract

Objective: To thoroughly analyze the correlation of thrombus volume with admission neurological deficit severity and postoperative clinical outcomes in patients with Acute Ischemic Stroke (AIS) treated by mechanical thrombectomy. Methods: A total of 119 AIS patients receiving mechanical thrombectomy were retrospectively enrolled. According to the 90-day mRS score after surgery, subjects were divided into a favorable prognosis group (n = 74) and an unfavorable prognosis group (n = 45). Baseline clinical data of the two groups were comprehensively collected, including age, gender, history of hypertension, diabetes mellitus, coronary heart disease, underlying heart disease, admission NIHSS score, onset-to-treatment time, vascular occlusion site, postoperative intracranial complications and thrombus volume. Spearman correlation analysis was adopted to evaluate the correlation between thrombus volume and NIHSS score, and multivariate Logistic regression analysis was performed to identify whether thrombus volume acted as an independent predictor of favorable prognosis. Results: Patients in the unfavorable prognosis group had significantly higher age, admission NIHSS scores, longer onset-to-treatment time, larger thrombus volume and higher incidence of intracranial hemorrhage complications compared with the favorable prognosis group (all p < 0.05). There were no statistically significant intergroup differences in gender, history of hypertension, diabetes mellitus, coronary heart disease, underlying heart disease and distribution of vascular occlusion sites (all p > 0.05). Conclusion: Thrombus volume is strongly correlated with the severity of admission neurological deficits and long-term clinical outcomes in AIS patients treated with mechanical thrombectomy.

Keywords: acute ischemic stroke , mechanical thrombectomy , thrombus volume , prognosis

Article Information

Received: 20 June 2026

Published: 2 July 2026

DOI: https://doi.org/10.54254/3049-5458/2026.35109

Article Type: Research Article

Cite this article

Sidik,N. (2026). Correlation between thrombus volume, neurological deficits and clinical prognosis in patients with acute ischemic stroke undergoing mechanical thrombectomy. Journal of Clinical Technology and Theory,4(4),24-30.

Data availability

The datasets used and/or analyzed during the current study will be available from the authors upon reasonable request.

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About this Journal

Journal: Journal of Clinical Technology and Theory

Volume: Vol.4, Issue 4

ISSN: 3049-5458 (Print) / 3049-5466 (Online)

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